Input sequence

Protein name Receptor tyrosine-protein kinase erbB-2
Organism Homo sapiens Length 1255
Disorder content 20.6% ProS content 16.5%
IDEAL IID00293 UniProt P04626

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 1255 1-16 17-640 641-652 653-675 676-690 691-992 993-997 998-1212 1213-1227 1228-1232 1233-1255 17-640 653-675 691-992 1213-1227 1233-1255 1-16 641-652 676-690 998-1212 1-16 641-652 676-690 998-1009 1015-1033 1041-1064 1086-1145 1151-1199 23-629 707-993 677-729 23-629 707-993 726-973 185-342 511-603 53-168 387-480 52-173 189-343 366-486 720-976 24-176 341-508 192-338 511-604 719-982 23-199 188-344 337-526 510-643 704-1028 3-21 453-467 658-675 1044-1063 1199-1217 653-675 772-794 1n8zC(1-581) 0.0 95.72% 3pp0A(2-286) 3e-163 98.61% 1z9iA(1-53) 4e-15 73.58% 1n8yC(1-592) 2e-160 84.35% 3pp0A(2-286) 7e-113 98.26% PF07714(7-251) 4e-47 40.8% PF00757(2-136) 3e-20 39.13% PF00757(12-81) 0.0003 33.33% PF01030(2-105) 4e-16 42.02% PF01030(12-104) 1e-05 38.95% PF01030 2e-43 154.9% PF00757 3.6e-94 323.4% PF01030 6.4e-31 113.3% PF07714 2.3e-133 453.6% 1ivoA1(4-146) 1e-49 46.41% 1ivoA2(1-168) 2e-49 39.88% 1ivoA3(1-147) 9e-42 50.0% 1ivoA3(4-82) 8e-12 25.53% 1nw1A(94-360) 2e-38 9.67% c.10.2 5.9e-46 143.8% g.3.9 1.8e-26 88.3% c.10.2 3.1e-45 150.9% g.3.9 1.5e-30 100.6% d.144.1 6.5e-76 263.2%

Sequence

MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLA
LTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLP
DLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTV
PWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARC
PSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVG
ILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYV
NQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQ
GGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV

Region:1-1255
Length:1255aa
Label:Full sequence
Reset:click