Input sequence

Protein name Major prion protein
Organism Homo sapiens Length 253
Disorder content 41.5% ProS content 29.6%
IDEAL NA UniProt P04156

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam RPS-BLAST:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 253 1-104 105-188 189-195 196-252 253-253 105-188 196-252 1-104 253-253 1-23 42-49 62-104 253-253 95-231 2-28 95-231 1-28 136-236 2-28 134-252 136-226 125-231 50-94 113-135 188-201 237-252 112-134 230-252 2kunA(6-142) 4e-53 99.27% 1skhA(4-30) 4e-07 74.07% 2kunA(6-142) 8e-29 99.27% 1skhA(3-30) 6e-09 71.43% PF00377(3-100) 5e-40 85.15% PF11587(4-30) 3e-10 85.19% PF00377 8.7e-70 242.4% 1i4mA(18-108) 1e-19 100.0% d.6.1 2.8e-47 153.7%

Sequence

MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP
HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA
VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV
NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
ILLISFLIFLIVG

Region:1-253
Length:253aa
Label:Full sequence
Reset:click