Input sequence

Protein name 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Organism Homo sapiens Length 888
Disorder content 13.9% ProS content 6.5%
IDEAL NA UniProt P04035

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 888 1-238 239-246 247-265 266-286 287-290 291-299 300-305 306-379 380-453 454-868 869-888 1-238 247-265 291-299 306-379 454-868 239-246 266-286 380-453 869-888 239-246 266-275 380-386 398-406 414-420 446-453 869-877 448-860 448-860 490-871 85-227 475-871 617-876 462-738 46-221 441-861 62-74 98-111 420-431 433-447 498-509 20-37 57-78 91-113 157-179 192-214 2r4fA(8-420) 0.0 99.76% 2r4fA(8-420) 6e-143 99.76% PF00368(1-367) 4e-112 57.59% PF12349(1-145) 5e-19 42.76% PF00368 0.0 1081.2% 1qaxA2(2-278) 1e-52 17.11% 1dq8A4(16-300) 7e-35 50.35% f.35.1 3.3e-06 23.1% d.179.1 4.6e-114 389.9%

Sequence

MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS
DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG
LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG
VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR
VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR
IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT
QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS
SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK
LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGV
AGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRAC
DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI
SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV
LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL
MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR
IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA

Region:1-888
Length:888aa
Label:Full sequence
Reset:click