Input sequence

Protein name Coagulation factor VIII
Organism Homo sapiens Length 2351
Disorder content 39.5% ProS content 20.8%
IDEAL NA UniProt P00451

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 2351 1-13 14-45 46-56 57-350 351-355 356-370 371-392 393-396 397-762 763-806 807-841 842-1683 1684-1813 1814-1817 1818-2042 2043-2046 2047-2351 14-45 57-350 371-392 397-762 807-841 1684-1813 1818-2042 2047-2351 1-13 46-56 356-370 763-806 842-1683 2043-2046 1-13 52-56 361-370 763-800 842-846 852-869 876-879 890-897 907-919 928-970 978-1022 1044-1054 1065-1098 1118-1134 1151-1163 1181-1220 1227-1245 1267-1272 1279-1287 1312-1314 1316-1334 1388-1393 1420-1424 1450-1455 1472-1475 1553-1556 1564-1569 1581-1598 1608-1629 1643-1683 2043-2046 20-744 1708-2351 20-744 1708-2351 2237-2332 2080-2175 469-572 92-197 218-349 1915-2039 2055-2185 2208-2342 2193-2346 2040-2190 21-212 1713-1889 399-584 1906-2036 596-733 216-390 16-210 209-353 399-579 586-736 1712-1893 1848-2048 2040-2190 2190-2348 8-18 1018-1032 1209-1226 1291-1301 2r7eA(1-693) 0.0 95.59% 2r7eB(1-644) 0.0 99.84% 2r7eA(1-693) 0.0 95.45% 2r7eB(1-644) 5e-169 99.84% PF00754(26-115) 6e-11 39.58% PF00754(26-115) 3e-09 34.34% PF07732(16-103) 5e-06 32.69% PF07732(16-103) 0.0001 33.96% PF00394 1.8e-06 26.3% PF07731 2.1e-06 24.5% PF00754 7.5e-39 139.7% PF00754 7.9e-43 152.9% 1czsA(2-158) 8e-48 42.04% 1czsA(2-159) 4e-40 41.14% 1sddA1(3-165) 2e-39 38.02% 1sddA1(2-162) 3e-26 31.35% 1kcwA1(1-192) 5e-35 39.58% 1gskA3(2-153) 7e-16 10.13% 1jv2A3(15-139) 2e-14 16.67% 1a65A3(26-201) 2e-07 11.86% b.6.1 3.7e-37 130.1% b.6.1 2.5e-31 105.5% b.6.1 6e-38 126.0% b.6.1 1.1e-39 133.6% b.6.1 1.9e-27 91.2% b.6.1 7.6e-44 153.5% b.18.1 1.5e-55 167.4% b.18.1 5.1e-61 201.5%

Sequence

MQIELSTCFFLCLLRFCFSATRRYYLGAVELSWDYMQSDLGELPVDARFPPRVPKSFPFN
TSVVYKKTLFVEFTDHLFNIAKPRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAV
GVSYWKASEGAEYDDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSH
VDLVKDLNSGLIGALLVCREGSLAKEKTQTLHKFILLFAVFDEGKSWHSETKNSLMQDRD
AASARAWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNH
RQASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNNE
EAEDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDWDYAPLVLA
PDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKTREAIQHESGILGPLLYGEVGDTL
LIIFKNQASRPYNIYPHGITDVRPLYSRRLPKGVKHLKDFPILPGEIFKYKWTVTVEDGP
TKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKESVDQRGNQIMSDKRNVILFSVFDE
NRSWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSINGYVFDSLQLSVCLHEVAYWYILS
IGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILGCHNSDFRNRG
MTALLKVSSCDKNTGDYYEDSYEDISAYLLSKNNAIEPRSFSQNSRHPSTRQKQFNATTI
PENDIEKTDPWFAHRTPMPKIQNVSSSDLLMLLRQSPTPHGLSLSDLQEAKYETFSDDPS
PGAIDSNNSLSEMTHFRPQLHHSGDMVFTPESGLQLRLNEKLGTTAATELKKLDFKVSST
SNNLISTIPSDNLAAGTDNTSSLGPPSMPVHYDSQLDTTLFGKKSSPLTESGGPLSLSEE
NNDSKLLESGLMNSQESSWGKNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTN
KTSNNSATNRKTHIDGPSLLIENSPSVWQNILESDTEFKKVTPLIHDRMLMDKNATALRL
NHMSNKTTSSKNMEMVQQKKEGPIPPDAQNPDMSFFKMLFLPESARWIQRTHGKNSLNSG
QGPSPKQLVSLGPEKSVEGQNFLSEKNKVVVGKGEFTKDVGLKEMVFPSSRNLFLTNLDN
LHENNTHNQEKKIQEEIEKKETLIQENVVLPQIHTVTGTKNFMKNLFLLSTRQNVEGSYD
GAYAPVLQDFRSLNDSTNRTKKHTAHFSKKGEEENLEGLGNQTKQIVEKYACTTRISPNT
SQQNFVTQRSKRALKQFRLPLEETELEKRIIVDDTSTQWSKNMKHLTPSTLTQIDYNEKE
KGAITQSPLSDCLTRSHSIPQANRSPLPIAKVSSFPSIRPIYLTRVLFQDNSSHLPAASY
RKKDSGVQESSHFLQGAKKNNLSLAILTLEMTGDQREVGSLGTSATNSVTYKKVENTVLP
KPDLPKTSGKVELLPKVHIYQKDLFPTETSNGSPGHLDLVEGSLLQGTEGAIKWNEANRP
GKVPFLRVATESSAKTPSKLLDPLAWDNHYGTQIPKEEWKSQEKSPEKTAFKKKDTILSL
NACESNHAIAAINEGQNKPEIEVTWAKQGRTERLCSQNPPVLKRHQREITRTTLQSDQEE
IDYDDTISVEMKKEDFDIYDEDENQSPRSFQKKTRHYFIAAVERLWDYGMSSSPHVLRNR
AQSGSVPQFKKVVFQEFTDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASR
PYSFYSSLISYEEDQRQGAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDV
DLEKDVHSGLIGPLLVCHTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRA
PCNIQMEDPTFKENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGH
VFTVRKKEEYKMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYSNKC
QTPLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKEPFSWIKVDLLAPMII
HGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVDSSGIKHNIFN
PPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKAISDAQITASSYFTNMFA
TWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFL
ISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRM
EVLGCEAQDLY

Region:1-2351
Length:2351aa
Label:Full sequence
Reset:click