Input sequence

Protein name E3 ubiquitin-protein ligase UBR5
Organism Homo sapiens Length 2799
Disorder content 40.6% ProS content 13.0%
IDEAL IID00191 UniProt O95071

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 2799 1-79 80-182 183-228 229-350 351-512 513-525 526-580 581-646 647-684 685-690 691-696 697-700 701-852 853-857 858-936 937-1071 1072-1144 1145-1149 1150-1289 1290-1318 1319-1351 1352-1358 1359-1443 1444-1452 1453-1500 1501-1787 1788-1807 1808-1815 1816-1862 1863-1914 1915-1961 1962-1965 1966-1970 1971-2019 2020-2064 2065-2180 2181-2316 2317-2393 2394-2414 2415-2419 2420-2423 2424-2434 2435-2441 2442-2496 2497-2799 1-79 183-228 351-512 526-580 647-684 701-852 858-936 1072-1144 1150-1289 1319-1351 1359-1443 1453-1500 1788-1807 1816-1862 1915-1961 1966-1970 2020-2064 2181-2316 2394-2414 2420-2423 2435-2441 2497-2799 80-182 229-350 513-525 581-646 691-696 937-1071 1290-1318 1444-1452 1501-1787 1863-1914 1971-2019 2065-2180 2317-2393 2415-2419 2424-2434 2442-2496 80-83 163-166 239-282 290-335 599-603 952-958 985-996 1025-1040 1290-1296 1314-1318 1501-1520 1610-1610 1641-1657 1688-1699 1707-1720 1741-1751 1776-1787 1863-1871 1905-1908 1971-1987 2065-2073 2091-2110 2360-2377 2388-2393 2415-2419 2424-2434 2442-2469 2693-2775 2393-2453 180-212 2693-2775 2393-2453 180-212 2615-2687 2218-2284 2504-2775 180-212 2389-2449 1191-1237 1177-1244 2375-2449 2486-2799 2528-2775 2218-2324 2393-2453 367-495 2239-2794 129-156 213-224 227-236 282-323 614-628 933-950 970-999 1138-1151 1396-1405 1524-1537 1567-1602 1641-1657 1662-1687 1726-1742 1759-1789 1879-1890 1972-1983 1986-1999 2076-2081 2329-2366 2420-2438 2489-2500 2776-2794 3pt3A(1-71) 3e-34 85.54% 1i2tA(1-61) 3e-14 100.0% 2qhoB(2-34) 1e-09 100.0% 3pt3A(1-71) 9e-20 81.93% 1i2tA(1-61) 1e-12 100.0% 2qhoB(2-34) 3e-07 100.0% 1gh8A(8-82) 9e-06 12.0% 3h1dA(15-74) 0.0002 25.0% PF00632(13-272) 2e-31 33.82% PF11547(3-35) 1e-09 84.85% PF00658(11-71) 1e-06 55.74% PF02207(11-63) 0.001 41.51% PF02207 7.1e-26 96.6% PF00658 5.4e-25 93.6% PF00632 3.3e-105 360.1% 1c4zA(92-331) 9e-58 26.8% 1nd7A(4-97) 6e-06 18.18% 1i2tA(1-61) 1e-15 100.0% b.69.5 1.6e-05 17.6% d.148.1 6.5e-82 245.5%

Sequence

MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
LLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETL
GRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVI
PASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASE
SYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLP
LERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDL
QWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLT
NEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCA
LYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNP
LYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQ
EPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVE
DVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVK
TGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQ
ENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPP
ISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVV
LEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVE
AIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPP
IAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKD
RKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIA
KAEISSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCG
LLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLT
ATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLE
PPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRL
DCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILS
VEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLA
STSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEE
QDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAA
ETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQ
SDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAAS
SAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMG
LIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALA
SAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNY
ALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTREL
LELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPF
EVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPT
KMSYAANLKNVMNMQNRQKKEGEEQPVLPEETESSKPGPSAHDLAAQLKSSLLAEIGLTE
SEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEV
KESKFRREMEKLRNQQSRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVT
FKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDRER
EREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGER
LYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADS
ILDLGLVDSSEKVQQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGK
NTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLR
QLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAE
HRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDES
GENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ
HLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV

Region:1-2799
Length:2799aa
Label:Full sequence
Reset:click