Input sequence

Protein name Sensor for unfolded proteins in the ER ire1
Organism Schizosaccharomyces pombe Length 1072
Disorder content 25.0% ProS content 7.4%
IDEAL NA UniProt O94537

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 1072 1-14 15-37 38-75 76-111 112-125 126-155 156-237 238-287 288-483 484-510 511-553 554-643 644-836 837-855 856-1072 15-37 76-111 156-237 288-483 511-553 644-836 856-1072 1-14 38-75 126-155 238-287 484-510 554-643 837-855 1-14 38-53 238-266 271-277 496-500 554-554 570-576 649-1070 78-234 649-1070 80-448 944-1069 660-933 654-938 943-1072 658-952 82-366 628-965 29-34 273-278 331-342 569-579 15-37 520-542 2rioA(5-394) 2e-98 43.82% 2be1A(6-132) 1e-11 29.38% 2rioA(5-394) 5e-104 43.59% 2be1A(8-272) 2e-19 19.36% PF06479(2-126) 3e-39 55.56% PF00069(7-253) 7e-14 30.9% PF00069 3.6e-45 160.7% PF06479 3.3e-74 257.1% 1nw1A(99-365) 3e-27 9.15% b.70.1 3.5e-11 34.8% d.144.1 2.9e-57 178.4%

Sequence

MKSLKGRLLFLRKFVFFSLLILLFAHGASSSSSSFNYFDKRTNGKANNELALFSPTADSP
SSVDGVLELPSAENVFAESSLYNAFIVATVDGSLHSYDRITGQELWSLFTNANPGLSYTK
DENSLLSSKFLSQSNFKSYNSTHGEFYSDSTLNISYLSDDDTVWFVEPIDGGILYAFNLQ
TGLVRLPHSIKDLVHASPIRLLNNNVFVGSKNTTLFTIDVSNGDIVSQYPSGHRYETHHS
VHNLGTKRDSVPSGADSDLSFKDPSGKKLSESLDLLDDFNYQVTVSNKSFVDIARTEYFI
TIYSDSNVILDLVYIDWTPTKNEIMYESFHSSSFDSKLALSSYDSSLHIVDTHSKFIKQN
IPLMSPAATVFDIVTLPHNKKIDKSQTPAKFPTSVLLRQPIDTYLETMFPQIARNKTEHV
YINHIGNAWFAMSERHYPLVSLAPEASFLYYNGFYIPLNSIFGLHSLMATPKPFFALPGL
PGYDIPSYVESEGSTKTLPSIGKKPIPLLDPNPISSTPISITFWVIMFLSVSFTIVTFFS
ILRIRSSEVRPLKSQKNTVSINNKIDTSKRRRKGKRRKRVSDEHSASSNFNEIESQASFE
QNQTLDILSENIVEIQDKSTDPLQKSLDSSLKSHLPEATVIQNTDGSVTVNSLTVYPEVI
GYGSHGTIVYRGVYEDREVAVKRVLMEFYDLASREITLLQQSDNHPNIVRYYCKQKSDQF
LYIVIELCKCNLSDLIEKPIAYDDLFKSIDLVSLLYQIAFGVSHLHSLDLVHRDLKPQNI
LLVVNNSPNLSKTRVRALISDFGLSKKLDFNQSSLRNTTFEAAGSYGWRSPEILSGSLSQ
QSKEIQVKTREGRIRQASHATDIFALGCIFYYTLTGGMHPFGSHYDCEGNILKGNYCLVH
LQSLGECGVLAADLIEDMIAFEPSKRPTIEVVLNHPLFWDYAKKLDFLIDVSDRFEVEER
DPPSPLLQMLENNSKSVIGENWTTCLHSSLVDNLGKYRKYDGSKILDILRVLRNKRHHYQ
DLPESVRRVLGDLPDGFTSYFVEKFPMLLLHCYHLVKDVLYEESQFKRYLEY

Region:1-1072
Length:1072aa
Label:Full sequence
Reset:click