Input sequence

Protein name Tyrosine-protein kinase JAK2
Organism Homo sapiens Length 1132
Disorder content 4.2% ProS content 2.2%
IDEAL NA UniProt O60674

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 1132 1-35 36-136 137-141 142-277 278-281 282-305 306-310 311-519 520-527 528-1128 1129-1132 36-136 142-277 282-305 311-519 528-1128 1-35 520-527 1129-1132 1-13 20-27 1129-1132 839-1131 536-809 39-513 535-1129 39-513 854-1123 551-805 401-481 545-805 849-1123 789-1119 538-804 397-520 38-123 141-261 390-565 534-834 834-1123 7-18 223-242 3e62A(1-291) 8e-170 99.32% 4fvqA(1-274) 3e-158 98.91% 4po6A(3-474) 1e-55 32.73% 4oliA(1-537) 2e-142 44.54% 4po6A(3-474) 6e-123 32.39% PF07714(6-254) 1e-44 39.34% PF07714(7-254) 2e-24 30.94% PF00017 0.00048 11.7% PF07714 1.2e-80 278.5% PF07714 2.1e-128 437.2% 1nw1A(35-349) 1e-35 5.9% 1nw1A(88-352) 3e-17 7.27% 1a81A1(5-123) 1e-10 17.74% 1wxaA1(4-87) 1e-07 11.49% 2aehA1(5-120) 6e-06 14.75% d.93.1 7.2e-25 83.3% d.144.1 3.9e-49 159.4% d.144.1 3.7e-70 226.2%

Sequence

MGMACLTMTEMEGTSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSG
EYVAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYF
PRWYCSGSNRAYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLG
MAVLDMMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQF
SQCKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNC
YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWA
MHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG

Region:1-1132
Length:1132aa
Label:Full sequence
Reset:click