Input sequence

Protein name DNA topoisomerase 2-alpha
Organism Gallus gallus Length 1553
Disorder content 28.0% ProS content 4.1%
IDEAL NA UniProt O42130

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 1553 1-32 33-428 429-433 434-944 945-949 950-1093 1094-1113 1114-1175 1176-1553 33-428 434-944 950-1093 1114-1175 1-32 429-433 1094-1113 1176-1553 8-13 29-32 429-433 1176-1181 1211-1224 1344-1354 1537-1553 435-1181 30-406 30-1176 714-1163 77-225 271-431 714-1175 1446-1545 432-1176 30-266 268-417 30-266 256-418 432-1182 341-353 1098-1112 1187-1205 1227-1250 1298-1308 1362-1384 1413-1432 1444-1455 1487-1494 1497-1523 1525-1536 4fm9A(2-726) 0.0 85.54% 1zxmA(1-373) 0.0 86.74% 4gfhA(1-1097) 0.0 48.01% PF00521(1-433) 7e-32 29.05% PF02518 4.7e-15 60.6% PF00204 1.4e-47 168.6% PF00521 2e-145 493.7% PF08070 2.1e-52 184.7% 1bgwA(1-674) 9e-146 41.42% 1pvgA2(1-239) 1e-48 56.07% 1pvgA1(2-138) 5e-45 42.0% d.122.1 1.2e-65 219.3% d.14.1 1.8e-46 150.3% e.11.1 1.4e-259 822.7%

Sequence

MELLDSPAPLRPLHDNPRLPKADGAQKRLSVERIYQKKTQLEHILLRPDTYIGSVETVTQ
QMWVFDEDVGLNCRDVTFVPGLYKIFDEILVNAADNKQRDKSMSCIKVTIDPENNTISVW
NNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTV
ETACREYKKLFKQTWTDNMGKAGEMTLKHFDGEDYTCVTFQPDLSKFKMTILDKDIVALM
SRRAYDIAGSTKDVKVFLNGKRLPVKGFRSYVDLYLKDKVDETGNALKVIHEEVNSRWEV
CLTLSEKGFQQVSFVNSIATTKGGRHVDYVADQIVTKLIDVVKKKNKNGVGVKPFQVKNH
MWIFVNSLIENPTFDSQTKENMTLQAKSFGSTCKLSEKFIKGAVGCGIVESILNWVKFKA
QTQLNKKCSAVKHTKIKGVPKLDDANDAGSKNSIDCTLILTEGDSAKTLAVSGLGVVGRD
KYGVFPLRGKMLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDRESLKSLRYGKIMIM
TDQDQDGSHIKGLLINFIHHNWPSLLRHNFLEEFITPIIKVSKNKEEIPFYSIPEFEEWK
SSTQNYNSWKIKYYKGLGTSTSKEAKEYFADMARHRIGFKYSGPEDDAAITLAFSKKKVE
ERKEWLTNFMEDRRQRNVHGLPEDYLYGKDTNYLTYNDFINKELVLFSNSDNERSIPSLV
DGLKPGQRKVLFTCFKRNDKREVKGAQLAGSVAEMSSYHHGEASLMMTIINLAQNFVGSN
NLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPVDDNVLRFLYDDNQRVEPE
WYMPIIPMVLINGAEGIGTGWSCKIPNFDIRETVNNIRCLLDGKEPLPMLPSYKNFKGTI
DELGPNQYVISGEVSILDSTTIEITELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYKE
YHTDTTVKFVVKMSEEKLAEAEAVGLHKVFKLQTNLTCNSMVLFDHVGFLKKYESPQDIL
KEFFELRLRYYGLRKEWLIGMLGAESAKLNNQARFILEKIDGKIVIENKPKKELIQVLIQ
RGYESDPVKAWKELQNKEEEEGDESGEESAAATGPDFNYLLNMPLWYLTKEKKDELCKQR
DNKDKELEDLKHKSPSDLWKEDLAAFVEELDAVEAKQMQDEMAGITGKPLKVKGGKQGGK
QKVTKAQLAEVMPSPHGIRVVPRVTAEMKAEAEKRIKKKIKSEKNESDEKQEGNSSGDKE
PSSLKQRLAQKRKAEQGTKRQTTLPFKPIKKMKRNPWSDSESDSESDDFEVPSKRERVVR
QAAAKIKPMVNSDSDADLTSSDEDSEYQENSEGNTDSDTTSKKKPPKAKAVPKEKKGKAP
KEKPLPDAVPVRVQNVAAESASQDPAAPPVSVPRAQAVPKKPAAAKKGSTAKDNQPSIMD
ILTKKKAAPKAPRRAQREESPPSEATAAVAKKPGPPRGRKATKRLTSSSDSDSDFGSRPS
KSVAAKKSKRDDDDSYSIDLTADSPAAAAPRTRPGRLKKPVQYLESSDEDDMF

Region:1-1553
Length:1553aa
Label:Full sequence
Reset:click