Input sequence

Protein name Toll-like receptor 4
Organism Homo sapiens Length 839
Disorder content 5.1% ProS content 4.8%
IDEAL NA UniProt O00206

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 839 1-18 19-610 611-617 618-629 630-633 634-825 826-839 19-610 618-629 634-825 1-18 611-617 630-633 826-839 4-18 611-617 630-633 826-839 27-547 672-815 476-627 27-599 671-815 677-814 676-814 674-815 304-556 49-191 145-273 29-255 260-624 669-817 116-128 203-213 292-303 636-651 634-656 2z63A(1-521) 0.0 97.31% 1fyxA(3-143) 2e-22 40.97% 2wfhA(33-181) 2e-06 26.45% 2z63A(1-549) 8e-92 89.55% 1fyxA(2-143) 5e-27 40.0% PF01582(2-133) 2e-13 35.97% PF01582 4.7e-45 160.3% 1fyvA(13-152) 8e-39 39.16% 1o6sA2(125-360) 1e-13 25.1% 1lqsL(7-139) 3e-10 9.09% 1lqsL(7-129) 0.0004 8.53% c.10.2 1.6e-36 114.6% c.10.2 1.6e-44 140.9% c.23.2 1.5e-35 123.4%

Sequence

MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLD
LSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALG
AFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHL
DLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSL
NVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAYLDYYLDDI
IDLFNCLTNVSSFSLVSVTIERVKDFSYNFGWQHLELVNCKFGQFPTLKLKSLKRLTFTS
NKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITMSSNFLG
LEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAG
NSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPY
KCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQL
LVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLML
LAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAA
NIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLR
QQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI

Region:1-839
Length:839aa
Label:Full sequence
Reset:click