Input sequence

Protein name Ryanodine receptor 1
Organism Rattus norvegicus Length 5035
Disorder content 14.5% ProS content 5.4%
IDEAL NA UniProt F1LMY4

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 5035 1-8 9-85 86-95 96-365 366-377 378-425 426-431 432-457 458-463 464-950 951-963 964-1060 1061-1067 1068-1308 1309-1422 1423-1500 1501-1510 1511-1751 1752-1757 1758-2044 2045-2088 2089-2214 2215-2226 2227-2262 2263-2268 2269-2390 2391-2410 2411-2529 2530-2535 2536-2827 2828-2845 2846-2941 2942-2960 2961-2967 2968-2984 2985-3019 3020-3028 3029-3291 3292-3297 3298-3379 3380-3385 3386-3468 3469-3503 3504-3581 3582-3587 3588-3679 3680-3689 3690-3729 3730-3758 3759-3861 3862-3865 3866-3868 3869-3894 3895-3899 3900-3909 3910-4251 4252-4284 4285-4307 4308-4319 4320-4365 4366-4366 4367-4537 4538-4584 4585-4623 4624-4747 4748-4758 4759-4943 4944-4948 4949-5031 5032-5035 9-85 96-365 378-425 432-457 464-950 964-1060 1068-1308 1423-1500 1511-1751 1758-2044 2089-2214 2227-2262 2269-2390 2411-2529 2536-2827 2846-2941 2961-2967 2985-3019 3029-3291 3298-3379 3386-3468 3504-3581 3588-3679 3690-3729 3759-3861 3866-3868 3895-3899 3910-4251 4285-4307 4320-4365 4538-4584 4624-4747 4759-4943 4949-5031 1-8 86-95 366-377 426-431 458-463 951-963 1061-1067 1309-1422 1501-1510 1752-1757 2045-2088 2215-2226 2391-2410 2828-2845 2942-2960 2968-2984 3020-3028 3292-3297 3380-3385 3469-3503 3680-3689 3730-3758 3869-3894 3900-3909 4252-4284 4308-4319 4367-4537 4585-4623 4748-4758 4944-4948 5032-5035 366-372 458-463 951-963 1309-1343 1371-1381 1387-1400 1421-1422 1756-1757 2059-2072 2391-2396 2402-2406 2951-2960 2968-2984 3024-3028 3380-3385 3498-3503 3730-3735 3752-3758 3869-3894 3900-3909 4252-4253 4263-4268 4308-4319 4374-4384 4411-4418 4437-4442 4468-4472 4608-4612 4944-4948 5032-5035 12-534 650-1210 2731-2936 1420-1566 3613-3639 12-534 650-1274 2731-2936 1075-1614 352-910 2613-2820 3613-3639 4381-4668 14-204 3878-4002 446-636 2158-2357 852-937 966-1058 2732-2820 2852-2936 1115-1204 222-366 213-392 441-645 660-798 851-945 965-1059 1086-1208 1430-1569 2156-2364 2731-2825 2851-2939 3508-4008 4379-4668 4758-4934 217-382 720-936 2551-2632 2739-2982 859-1082 1028-1206 1429-1571 4055-4135 217-394 4078-4135 4511-4572 2-11 501-514 690-709 1317-1331 1785-1801 1873-1923 1987-1996 2046-2055 2073-2087 2284-2295 2388-2402 2821-2838 3126-3140 3286-3300 3371-3390 3421-3437 3681-3691 3735-3760 3908-3922 4012-4025 4255-4289 4300-4333 4340-4350 4394-4424 4480-4497 4505-4543 4562-4577 4592-4614 4838-4853 4912-4930 1863-1927 3534-3561 4285-4307 4320-4338 4343-4365 4556-4578 4646-4668 4787-4809 4835-4857 4916-4935 4uweA(3-523) 0.0 96.75% 4uweA(583-1053) 0.0 80.6% 4uweA(1792-1973) 7e-95 84.06% 4uweA(1053-1176) 7e-64 82.31% 2bcxB(1-27) 4e-08 100.0% 4uweA(3-523) 0.0 96.75% 4uweA(583-1121) 0.0 72.26% 4uweA(1792-1973) 4e-122 83.01% 4uweA(584-1093) 1e-72 18.68% 4uweA(591-1131) 2e-36 17.3% 4uweA(1806-1971) 1e-30 24.88% 2bcxB(1-27) 2e-07 100.0% PF06459(3-270) 2e-32 47.68% PF08709(5-219) 2e-31 42.53% PF08454(4-113) 9e-25 55.2% PF01365(5-192) 2e-24 41.75% PF01365(2-182) 2e-19 34.13% PF02026(2-87) 1e-22 54.65% PF02026(2-94) 1e-19 45.16% PF02026(2-90) 5e-18 43.82% PF02026(2-92) 7e-16 46.15% PF00622(32-117) 2e-07 35.87% PF02815(1-139) 9e-06 25.17% PF02815 9.7e-77 265.5% PF01365 1.1e-96 331.7% PF00622 1.2e-36 132.3% PF02026 2.4e-63 221.0% PF02026 1e-60 212.3% PF00622 9.2e-39 139.4% PF00622 3.5e-38 137.4% PF01365 4e-89 306.7% PF02026 4.5e-62 216.8% PF02026 3.5e-49 174.0% PF08454 4.2e-237 798.2% PF06459 2.5e-116 397.1% PF00520 4.8e-07 34.0% 1n4kA2(1-132) 8e-32 18.45% 1a8iA(235-452) 4e-20 15.15% 2i76A1(10-102) 2e-18 10.75% 1b7eA(1-250) 4e-15 5.95% 1b7eA(1-238) 5e-10 7.14% 2fbeA1(14-183) 1e-12 15.14% 2fbeA1(44-188) 1e-10 11.41% 1wlzA1(1-82) 0.0003 14.63% b.42.6 5.2e-70 233.0% a.39.1 3.3e-06 22.1% a.207.1 0.00094 11.0%

Sequence

MGDGGGEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVP
PDLAICCFILEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSRMYLS
CLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERY
LHLSTASGELQVDASFMQTLWNMNPICSCCEEGFVTGGHVLRLFHGHMDECLTISPSDSD
DQRRLVYYEGGPVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGL
VVVDASKAHTKATSFCFRISKEKLDVAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTY
AAPDPKALRLGVLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIYSTAGLYNQFIKGLD
SFSGKPRGSGPPAGSALPIEGVILSLQDLIGYFEPPSEELQHEEKQTKLRSLRNRQSLFQ
EEGMLSLVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYELLASLIRGNRTNCAL
FSTNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKV
LDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQY
GKWYFEVMVDEVAPFLTAQATHLRVGWALSEGYSPYPGGGEGWGGNGVGDDLYSYGFDGL
HLWTGHVARPVTSPGQHLLGPEDVVSCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFP
VVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLQPIKEYRREGPRGPHL
VGPSRCLSHLDFVPCPVDTIQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDD
NKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTY
MMNNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNP
RLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVDSQSRGDRARIFRAEK
SYAVQSGRWYFEFEAVTTGRELGWARPELRPDVELGADDLAYVFNGHRGQRWHLGSEPFG
RPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVG
HLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPLEHPHYEVARM
DGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAGATPLASPGLQPPAE
DEARAAEPDTDYENLRRSAGGWGEAEAGKDGTAKEGTPGGAAQPGVEAQPARAENEKDAT
TEKNKKRGFLFKAKKVAMMTQPPSTPALPRLPRDVVPADNRDDPEIILNTTTYYYSVRVF
AGQEPSCVWVGWVTPDYHQHDMSFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDF
VSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQN
VVQFDLRPGANIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLHVDTRRA
GERLGWAVQCQEPLMMMALHIPEENSEPYIHLKRAQLDPRDLRDYRDTKFDSESSDSDQT
PQPGCYHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTEE
TRAITLFPPGRSAEDGPRRHGLPGVGVTTSLRPPHHFSPPCFVVALPAAGAAEAPARLSP
AIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGVFSDEDVK
QILKMIEPEVFTEEEEVEEEEEEEEEDEEEKEEDEEEEAHEKEDEEKEEAEEAAEEEKEE
LEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQSNQRGRYGLLM
KAFTMSAAETARRTREFRSPPQEQINMLLQFKNGADEEDCPLPEEIREDLVNFHQDLLAH
CGIQLEGEEEEPEEESTLGSRLMSLLEKVRLVKKKEEKPEEEPAAEEHKPQSLQELVSHT
VVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISLSSVEDTMSLLECLGQ
IRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESK
EIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVI
DNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFV
NGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVRRDR
RREHFGEEPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLV
PLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHV
LDVGFLPDMRAAASLDTATFSRRWALALTRYLCAVLPLITKCAPLLRGTEHRAIMVDSML
HTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKL
LTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRIAMPCL
CAIAGALPPDYVDASYSSKTEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFAEYAH
EKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTV
EKAREGEEEKTEKKKTRKISQTAQTYDPREGYNPQPPDLSVVTLSRELQAMAEQLAENYH
NTWGRKKKQELEAKGGGSHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRHGKD
MELDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILL
PLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPA
VVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVK
GVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTRNPYV
EKLRPALGECLARLAAAMPVAFLEPELNEYNACSVYTTKSPRERAILGLPNSVEEMCPDI
PVLERLMAEIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPP
CTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLRSHFIPTIG
RLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRSAW
PRLPPSPSSSFSLPSPSELGRWLMKDHGHQLYEESFTVPLILDNAAFPLARNQSRAIGCA
GVVRSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIVLAKARYA
LKDTDEEVREFLQNNLNLQGKVEGSPSLRWQMALYRGVPGREEDADDPEKIVRRVQEVSA
VLYHLDQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKASW
ILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYL
YMAYADIMAKSCHLEEGGENVEEGGEEEEVEVSFEEKEMEKQRLLYQQSRLHNRGAAEMV
LQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTC
RWPHKTLSQREGQEERVMKVQTSGTLVIINRQNGEKVMADDEFTQDLFRFLQLLCEGHNN
DFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSV
AKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELL
DLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAF
QDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINCEEFANRFQEPAR
DIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILDYFRPYLGRIEIMGASRRIERIYFEI
SETNRAQWEMPQVKESKRQFIFDVVNEGGESEKMELFVSFCEDTIFEMQIAAQISEPEGE
PEEDDDEGAEEAEEGAAGPDGSGSAAAAGVWTWLATAAGRTLRGLSYRSLRRRVRRLRRL
TAREAATAVAVLLWAMVARAGGAGAGAAAGVLRLLWGSLFGGGLVDSAKKVTVTELLAGM
PDPTGDEVHGQQPSGAGSDAEGEGQGEGEGDAAEGVGDEEVAADQAGTGGADRTVAVADG
SPFRPEGAGGLGDMGDTTPVEPPTPEGSPILKRKLGVDGEEEEPQPEPEPEPEPEPEKAD
TENGEKEVPEPPPEPPKKAPPPPPPKKEEAGGAGLEEFWGELEVQRVKFLNYLSRNFYTL
RFLALFLAFAINFILLFYKVSDSPPGEDDIEGSGAGDMSGAGSGDGSGWGSRASEEVEGD
EDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLE
FDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLG
MDLASLEITAHNERKPDPPPGLLTWIMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLG
HYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKF
YNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFF
FVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEE
HNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG

Region:1-5035
Length:5035aa
Label:Full sequence
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