Input sequence

Protein name Ryanodine receptor 1
Organism Mus musculus Length 5035
Disorder content 14.6% ProS content 6.9%
IDEAL NA UniProt E9PZQ0

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 5035 1-10 11-86 87-95 96-368 369-379 380-419 420-431 432-462 463-466 467-950 951-956 957-1064 1065-1069 1070-1308 1309-1423 1424-1501 1502-1512 1513-1754 1755-1769 1770-2047 2048-2092 2093-2217 2218-2224 2225-2384 2385-2413 2414-2829 2830-2852 2853-2944 2945-2953 2954-2983 2984-2989 2990-2993 2994-3024 3025-3034 3035-3226 3227-3237 3238-3294 3295-3300 3301-3456 3457-3505 3506-3625 3626-3629 3630-3680 3681-3694 3695-3732 3733-3760 3761-3859 3860-3876 3877-4248 4249-4284 4285-4307 4308-4319 4320-4365 4366-4537 4538-4583 4584-4624 4625-4743 4744-4759 4760-4941 4942-4948 4949-5031 5032-5035 11-86 96-368 380-419 432-462 467-950 957-1064 1070-1308 1424-1501 1513-1754 1770-2047 2093-2217 2225-2384 2414-2829 2853-2944 2954-2983 2994-3024 3035-3226 3238-3294 3301-3456 3506-3625 3630-3680 3695-3732 3761-3859 3877-4248 4285-4307 4320-4365 4538-4583 4625-4743 4760-4941 4949-5031 1-10 87-95 369-379 420-431 463-466 951-956 1065-1069 1309-1423 1502-1512 1755-1769 2048-2092 2218-2224 2385-2413 2830-2852 2945-2953 2984-2989 3025-3034 3227-3237 3457-3505 3681-3694 3733-3760 3860-3876 4249-4284 4308-4319 4366-4537 4584-4624 4744-4759 4942-4948 5032-5035 1-3 376-379 420-426 463-466 951-956 1065-1069 1309-1348 1368-1381 1387-1396 1409-1423 1755-1769 2058-2075 2385-2398 2404-2407 2830-2835 2848-2852 2945-2953 2984-2989 3025-3034 3227-3237 3457-3476 3492-3495 3500-3505 3691-3694 3733-3739 3754-3760 3860-3876 4249-4255 4263-4269 4308-4319 4374-4384 4389-4392 4451-4456 4469-4474 4607-4611 4744-4748 4942-4948 5032-5035 12-534 650-1211 2735-2940 1421-1572 3615-3641 12-534 650-1275 2735-2940 1075-1750 2617-2824 3615-3641 14-204 4381-4668 3878-4002 446-636 2160-2359 852-937 966-1058 2736-2824 2856-2940 1086-1205 222-366 213-392 441-645 660-798 851-945 965-1059 1086-1209 1431-1571 2158-2366 2735-2829 2855-2943 3510-4008 4379-4668 4758-4934 217-382 720-936 2554-2636 2743-2986 859-1082 1028-1207 1430-1583 3339-3494 4055-4135 217-394 4078-4135 2-11 501-514 690-709 1318-1332 1340-1349 1787-1798 1875-1925 1989-1998 2048-2057 2069-2092 2286-2297 2390-2404 2825-2842 3130-3144 3290-3304 3375-3394 3683-3693 3737-3762 3908-3922 4012-4025 4255-4289 4300-4351 4395-4440 4480-4497 4505-4543 4562-4577 4592-4614 4838-4853 4912-4930 1872-1929 3536-3563 4285-4307 4320-4338 4343-4365 4556-4578 4646-4668 4787-4809 4835-4857 4916-4935 4uweA(3-523) 0.0 96.37% 4uweA(583-1053) 0.0 81.67% 4uweA(1792-1973) 2e-95 84.54% 4uweA(1053-1181) 2e-67 83.55% 2bcxB(1-27) 4e-08 100.0% 4uweA(3-523) 0.0 96.37% 4uweA(583-1121) 0.0 73.2% 4uweA(1792-1973) 2e-122 83.5% 4uweA(584-1160) 2e-78 17.55% 4uweA(1806-1971) 7e-31 24.88% 2bcxB(1-27) 2e-07 100.0% PF08709(5-219) 2e-31 42.53% PF06459(3-270) 4e-30 47.02% PF08454(4-113) 9e-25 55.2% PF01365(5-192) 2e-24 41.75% PF01365(2-182) 2e-19 34.13% PF02026(2-87) 1e-22 54.65% PF02026(2-94) 1e-19 45.16% PF02026(2-90) 5e-18 43.82% PF02026(2-92) 7e-16 46.15% PF00622(1-117) 7e-10 34.96% PF02815(1-139) 9e-06 25.17% PF02815 2.9e-76 263.9% PF01365 1.1e-96 331.7% PF00622 8.2e-37 132.9% PF02026 2.8e-63 220.8% PF02026 1e-60 212.3% PF00622 5.1e-44 156.8% PF00622 7.3e-42 149.7% PF01365 4e-89 306.7% PF02026 3.5e-62 217.2% PF02026 5e-51 180.1% PF08454 3.7e-255 858.2% PF06459 7e-117 398.9% PF00520 4.8e-07 34.0% 1n4kA2(1-132) 6e-32 17.86% 1a8iA(235-452) 1e-21 14.72% 2i76A1(10-102) 2e-19 10.75% 1b7eA(1-250) 2e-16 5.95% 1b7eA(1-238) 3e-10 7.14% 2fbeA1(14-183) 5e-15 15.14% 2fbeA1(44-188) 6e-11 11.95% 1ak6A(21-171) 4e-14 13.41% 1wlzA1(1-82) 0.0003 14.63% b.42.6 1.1e-69 231.9% a.39.1 3.3e-06 22.1%

Sequence

MGDGGGEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVP
PDLAICCFILEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSRMYLS
CLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERY
LHLSTASGELQVDASFMQTLWNMNPICSGCEEGFVTGGHVLRLFHGHMDECLTISPSDSD
DQRRLVYYEGGPVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLGLTEDQGL
VVVDASKAHTKATSFCFRISKEKLDVAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTY
AAPDPKALRLGVLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIYSTAGLYNQFIKGLD
SFSGKPRGSGPPAGSALPIEGVILSLQDLIGYFEPPSEELQHEEKQTKLRSLRNRQSLFQ
EEGMLSLVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYELLASLIRGNRTNCAL
FSTNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKV
LDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQY
GKWYFEVMVDEVAPFLTAQATHLRVGWALSEGYSPYPGGGEGWGGNGVGDDLYSYGFDGL
HLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFP
VVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLQPIKEYRREGPRGPHL
VGPSRCLSHLDFVPCPVDTIQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDD
NKRLHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTY
MMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNP
RLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVDSQSRGDRARIFRAEK
SYAVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADDLAYVFNGHRGQRWHLGSEPF
GRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFRDIEIGDGFLPVCSLGPGQV
GHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPLEHPHYEVAR
MDGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAGATPLASPGLQPPA
EDEARAAEPDTDYENLRRSAGGWGEAEGGKDGTAKEGTPGGTAQAGVEAQPARAENEKDA
TTEKNKKRGFLFKAKKVAMMTQPPSTPALPRLPRDVVPADNRDDPEIILNTTTYYYSVRV
FAGQEPSCVWVGWVTPDYHQHDMSFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGD
FVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQ
NVVQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVDTRR
AGERLGWAVQCQEPLMMMALHIPEENRCMDILELSERLDLQRFHSHTLSLYRSVCALGNN
RVAHALCSHVDQAQLLHALEDARLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLT
PETRAITLFPPGRSAEDGPRRHGLPGVGVTTSLRPPHHFSPPCFVVALPAAGATEAPARL
SPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGVFSDED
VKQILKMIEPEVFREEEEVEEEGEEEEEDEEEKEEDEEEEAHEKEDEEKEEAEDAAEEEK
EELEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAECYVDKMQGNQRGRYGL
LMKAFTMSAAETARRTREFRSPPQEQINMLLHFKNGADEEECPLPEEIRQELVNFHQDLL
AHCGIQLEGEEEEPEEESTLGSRLMSLLEKVKLVKKTEEKPEEEPAPEEHKPQSLQELVS
HTVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISVSSVEDTMSLLECL
GQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGE
SKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAAS
VIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAV
FVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVRR
DRRREHFGEEPPEENRVHLGHAIMSFYAALIDLLGRCAPETHLIQAGKGEALRIRAILRS
LVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLL
HVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMV
DSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKM
PLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRIA
MPCLCAIAGALPPDYVDASYSSKTEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFA
EYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAW
EWTVEKAREGEEEKTEKKKTRKISQTAQTYDPREGYNPQPPDLSVVTLSRELQAMAEQLA
ENYHNTWGRKKKQELEAKGGGSHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTR
GLKDMELDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFA
KILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGT
DAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQAR
TQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTR
NPYVEKLRPALGECLARLAAAMPVAFLEPELNEYNACSVYTTKSPRERAILGLPNSVEEM
CPDIPVLERLMAEIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAG
APPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLRSHFI
PTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNN
RAHWLTEPNPNAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKSKMA
KAGDVQSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIVLAKAR
YALKDTDEEVREFLQNNLNLQGKVEGSPSLRWQMALYRGVPGREEDADDPEKIVRRVQEV
SAVLYHLDQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKA
SWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDED
YLYMAYADIMAKSCHLEEGGENGEEGGEEEEVEVSFEEKEMEKQRLLYQQSRLHNRGAAE
MVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQ
TCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNN
DFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSV
AKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELL
DLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAF
QDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINCEEFANRFQEPAR
DIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEI
SETNRAQWEMPQVKESKRQFIFDVVNEGGESEKMEMFVSFCEDTIFEMQIAAQISEPEGE
PEEDEDEGAEEAEEGAAGSDGSGSAAAAGVWVWLAATAGRTLRGLSYRSLRRRVRRLRRL
TAREAATAVAALLWALVTRAGGAGAGAAAGALRLLWGSLFGGGLVDSAKKVTVTELLAGM
PDPTGDEVHGQQPSGAGSDAEGEGEGEGEGDAADGAGDEEAAADQAGTGGADGAVAVADG
SPFRPEGAGGLGDMGDTTPVEPPTPEGSPILKRKLGVDGEEEEPPPEPEPEPEPEPEKAD
TENGEKEVPEPPPEPPKKTPPPPPPKKEEAGGAGLEEFWGELEVQRVKFLNYLSRNFYTL
RFLALFLAFAINFILLFYKVSDSPPGEDDIEGSGAGDMSGAGSGDGSGWGSRAGEEVEGD
EDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLE
FDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLG
MDLASLEITAHNERKPDPPPGLLTWIMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLG
HYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKF
YNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFF
FVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEE
HNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS

Region:1-5035
Length:5035aa
Label:Full sequence
Reset:click