Input sequence

Protein name Ryanodine receptor 2
Organism Rattus norvegicus Length 4953
Disorder content 14.1% ProS content 7.3%
IDEAL NA UniProt B0LPN4

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 4953 1-8 9-85 86-98 99-375 376-385 386-434 435-450 451-457 458-470 471-727 728-732 733-952 953-964 965-1060 1061-1066 1067-1076 1077-1281 1282-1286 1287-1319 1320-1408 1409-1488 1489-1495 1496-1849 1850-1880 1881-2001 2002-2045 2046-2347 2348-2366 2367-2787 2788-2806 2807-2900 2901-2908 2909-2937 2938-2943 2944-2975 2976-2979 2980-2987 2988-3178 3179-3188 3189-3334 3335-3339 3340-3418 3419-3451 3452-3624 3625-3637 3638-3675 3676-3700 3701-4189 4190-4264 4265-4287 4288-4298 4299-4305 4306-4466 4467-4510 4511-4540 4541-4663 4664-4673 4674-4678 4679-4949 4950-4953 9-85 99-375 386-434 451-457 471-727 733-952 965-1060 1077-1281 1287-1319 1409-1488 1496-1849 1881-2001 2046-2347 2367-2787 2807-2900 2909-2937 2944-2975 2988-3178 3189-3334 3340-3418 3452-3624 3638-3675 3701-4189 4265-4287 4299-4305 4467-4510 4541-4663 4679-4949 1-8 86-98 376-385 435-450 458-470 728-732 953-964 1067-1076 1282-1286 1320-1408 1489-1495 1850-1880 2002-2045 2348-2366 2788-2806 2901-2908 2938-2943 2980-2987 3179-3188 3335-3339 3419-3451 3625-3637 3676-3700 4190-4264 4288-4298 4306-4466 4511-4540 4664-4673 4950-4953 1-8 86-98 383-385 435-450 458-470 728-732 953-961 1067-1076 1282-1286 1320-1349 1362-1370 1378-1389 1404-1408 1850-1855 1866-1880 2014-2029 2348-2366 2794-2796 2938-2943 2980-2987 3179-3188 3335-3339 3419-3429 3444-3451 3676-3680 3697-3700 4206-4210 4218-4221 4229-4264 4288-4298 4319-4328 4348-4353 4364-4382 4406-4409 4425-4430 4664-4666 4950-4953 10-537 653-1270 1398-1556 2691-2895 3559-3585 9-537 653-1349 2690-2895 1080-1776 2572-2781 2799-3295 3559-3585 4471-4643 4018-4071 4445-4585 13-207 3816-3941 2691-2781 854-940 969-1061 2811-2895 449-641 2113-2315 1092-1200 746-793 228-365 219-399 444-648 663-801 854-948 968-1062 1091-1214 1416-1555 2111-2322 2690-2784 2810-2898 3455-3946 4319-4585 4676-4852 223-389 2698-2940 723-1016 3289-3440 2509-2591 1030-1226 1389-1561 3944-4070 223-398 4018-4075 694-712 1636-1646 1846-1861 2407-2417 2488-2501 3679-3688 4205-4214 4243-4260 4296-4304 4326-4337 4346-4364 4397-4444 4753-4771 4830-4848 4265-4287 4484-4503 4557-4579 4696-4718 4753-4775 4834-4853 4jkqA(1-499) 0.0 92.23% 4uweA(583-1109) 0.0 55.89% 4uweA(1047-1181) 1e-39 53.46% 4etvA(1-183) 5e-91 86.83% 2bcxB(1-27) 7e-07 88.89% 4uweA(1-523) 0.0 68.29% 4uweA(583-1160) 0.0 51.48% 4uweA(1792-1973) 4e-125 58.25% 4uweA(584-1176) 1e-75 17.63% 4uweA(1806-1973) 3e-41 22.64% 4uweA(707-1166) 1e-35 15.13% 2bcxB(1-27) 7e-08 88.89% 1k8kE(2-171) 1e-07 13.87% 2fceA(11-65) 2e-06 27.27% PF06459(130-270) 1e-36 54.61% PF08709(5-218) 1e-32 43.18% PF08454(4-114) 5e-31 56.35% PF02026(2-92) 8e-26 54.95% PF02026(1-87) 6e-23 55.17% PF02026(2-94) 3e-21 45.16% PF02026(2-92) 3e-16 46.15% PF01365(5-194) 2e-24 39.59% PF01365(2-182) 2e-23 34.29% PF00622(2-107) 3e-05 31.25% PF00622(66-113) 0.001 41.67% PF02815(1-130) 0.0002 24.46% PF02815 3.6e-81 280.2% PF01365 1.3e-96 331.5% PF00622 1.4e-36 132.1% PF02026 3e-61 214.1% PF02026 8.3e-63 219.2% PF00622 6.6e-43 153.1% PF00622 3.4e-34 124.2% PF01365 3.7e-84 290.2% PF02026 7.4e-65 226.0% PF02026 5.5e-33 120.2% PF08454 7.9e-269 903.6% PF06459 1.1e-140 477.9% PF00520 1.3e-07 35.8% 1n4kA2(1-132) 4e-34 17.26% 1b7eA(1-249) 1e-22 6.43% 1a8iA(235-536) 8e-22 13.17% 1ak6A(21-172) 2e-20 15.0% 2i76A1(10-102) 7e-20 12.9% 2fnjA1(10-214) 2e-15 12.84% 2fbeA1(15-182) 2e-06 11.48% 1ij5A(100-230) 4e-09 16.79% b.42.6 7.2e-71 235.9% a.39.1 2.1e-11 35.8%

Sequence

MADAGEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPP
DLSICTFVLEQSLSVRALQEMLANTVEKSEGKFMMKTAQGGGHRTLLYGHAILLRHSYSG
MYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVS
SERYLHLSYGNSSWRVDAAFQQTLWSVAPISSGSEAAQGYLIGGDVLRLLHGHMDECLTV
PSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLS
LMEDKNLLLMDKEKADVKSTAFAFRSSKEKLDAGVRKEVDGMGTSEIKYGDSICYIQHVD
TGLWLTYQAVDVKSARMGSIQRKAIMHHEGHMDDGLNLSRSQHEESRTARVIRSTVFLFN
RFIRGLDALSKRAKLPTVDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQN
LFQEEGMINLVLECIDRLHVYSSAAHFADVAGREAGESWKSILNSLYELLAALIRGNRKN
CAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRN
HKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGVSEGS
AQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGF
DGLHLWSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGL
FFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAACYEAVLPKEKLKVEHSREYKQERTYT
RDLLGPTVSLTQAAFTPVPVDTSQIVLPPHLERIRERLAENIHELWVMNKIELGWQYGPV
RDDNKRQHPCLVEFCKLPEQERNYNLQMSLETLKTLLALGCHVGIADEHAEEKVKKMKLP
KNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGIQQDVKNR
RNPRLVPYTLLDDRTKKSNKDSLREAVRTLLGYGYHLEAPDQDHASRAEVCSGTGERFRI
FRAEKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDLELGSDERAFAFDGFKAQRWHQ
GNEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFDVGDGFIPVCSL
GVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSNHEH
IEVTRIDGTIDSSPCLKVTQKSFGSQNSNTDIMFYRLSMPIECAEVFSKSVAGGIPGAGF
YGPKNDLEDFDVDSDFEVLMKTAHGHLVPDRMDKDKETPKPEFNNHKDYAQEKPSRLKQR
FLLRRTKPDYSTSHSARLTEDVLADDRDDYEYLMQTSTYYYSVRIFPGQEPANVWVGWIT
SDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGESMSPGQGRNNSNGLE
IGCVVDAASGLLTFIANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGRIKNVMPL
SAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISERQGWLVQCLDPLQ
FMSLHIPEENRSVDILELTEQEELLQFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLL
YAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMTEETKSITLFPDENKKH
GLPGIGLSTSLRPRMCFSSPSFVSISNECYQYSPEFPLDILKAKTIQMLTEAVKEGSLHA
RDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSVFKEAATPEEEGGAPEK
EISIDDSKLEVKEEAKAGKRPKEGLLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAF
SDDFVAKLQDNQRFRYNEVMQALNMSAALTARKEFRSPPQEQINMLLNFKDDKSECPCPE
EIRDQLLDFHEDLMTHCGIELDEDGSLDGSNDLTIRGRLLSLVEKVTYLKKKQAEKPVAS
DSRKSSSLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVRALPKTYTING
VSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHET
VMEVMVNVLGGGESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLA
SPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCQMLVSKGYPDIGW
NPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAMEEA
IKIAEDPSRDGPSPTSGSSKTLDAEEEEDDTIHMGNAIMTFYAALIDLLGRCAPEMHLIH
AGKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGKVVEPDMSAGFCPDHKAAMVL
FLDRVYGIEVQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLCTAVLPLLTR
CAPLFAGTEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCLLSICGQLRPSMMQHLLR
RLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWSNFGAASEEELHLSRKLFWGIFD
ALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSMMEKQSSMDSEGNFNPQPVDTSN
ITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKIQPLMKPYKLLSEKEKEI
YRWPIKESLKTMLAWGWRIERTREGDSMALYNRTRRISQTSQVSIDAAHGYSPRAIDMSN
VTLSRDLHAMAEMMAENYHNIWAKKKKMELESKGGGNHPLLVPYDTLTAKEKAKDREKAQ
DIFKFLQISGYAVSRGFKDLDLDTPSIEKRFAYSFLQQLIRYVDEAHQYILEFDGGSRSK
GEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLCTGGHASNKEKEMVTSLFCK
LGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLDSVKSALRAFLDNAAEDLEK
TMENLKQGQFTHTRSQPKGVTQIINYTTVALLPMLSSLFEHIGQHQFGEDLILEDVQVSC
YRILTSLYALGTSKSIYVERQRSALGECLAAFAGAFPIAFLETHLDKHNVYSIYNTRSSR
ERAALSLPANVEDVCPNIPSLEKLMTEIIELAESGIRYTQMPHMMEVVLPMLCSYMSRWW
EHGPENHPERAEMCCTALNSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAVFSQPIINKV
KPQLLKTHFLPLMEKLKKKAAMVVSEEDHLKAEARGDMSEAELLILDEFTTLARDLYAFY
PLLIRFVDYNRAKWLKEPNPEAEELFRMVAEVFIYWSKSHNFKREEQNFVVQNEINNMSF
LITDTKSKMSKAAISDQERKKMKRKGDRYSMQTSLIVAALKRLLPIGLNICAPGDQELIA
LAKNRFSLKDTEEEVRDVIRSNIHLQGKLEDPAIRWQMALYKDLPNRAEDTSDPERTVER
VLDIANVLFHLEQVEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRAVNLFLQ
GYEKSWIETEEHYFEDKLIEDLAKPGSELPEEDEAMKRVDPLHQLILLFSRTALTEKCKL
EEDFLYMAYADIMAKSCHDEEDDDGEEEVKSFEVTGSQRSKEKEMEKQKLLYQQARLHDR
GAAEMVLQTFSASKGETGPMVAATLKLGIAILNGGNSTVQQKMLDYLKEKKDVGFFQSLA
GLMQSCSVLDLNAFERQNKAEGLGMVTEEGSGEKVLQDDEFTCDLFRFLQLLCEGHNSDF
QNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDIIDEQGQRNFSKAIQVAK
QVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKELMDL
QKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDTFKE
YDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPAKDI
GFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYFEISE
SSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQISESDLNER
SANKEESEKERPEEQAPRMGFFSLLTVQSALFALRYNVLTLVRMLSLKSLKKQMKRMKKM
TVKDMVSAFFSSYWSVFVTLLHFVASVCRGFFRIVSSLLLGGSLVEGAKKIKVAELLANM
PDPTQDEVRGDEEEGERKPLESALPSEDLTDLKELTEESDLLSDIFGLDLKREGGQYKLI
PHNPNAGLSDLMTNPIPVPEVQEKFQEQKVKEEKEGKEETKSEPEKAEGEDGEKEEKAKD
DKGKQKLRQLHTHRYGEPEVPESAFWKKIIAYQQKLLNYFARNFYNMRMLALFVAFAINF
ILLFYKVSTSSVVEGKELPTRTSSDAAKVTTSLDSSPHRIIAVHYVLEESSGYMEPTLRI
LAILHTIISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLV
INTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFSDAREKKKPKKDSSL
SAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLR
TILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYM
FHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELR
DQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHT
GQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN

Region:1-4953
Length:4953aa
Label:Full sequence
Reset:click